Emap2lig

Emap2lig is a ligand structure modeling tool that integrates cryo-EM density information with a diffusion-model-based structure prediction pipeline.

Kihara Lab website: https://kiharalab.org/

Kihara Lab EM server: https://em.kiharalab.org/algorithm/Emap2lig

Github: https://github.com/kiharalab/Emap2lig

License

This repository uses a custom license. See the LICENSE file for full terms.

Citations

Please cite our paper:

@article{li2026direct,
  title        = {Direct Detection and Atomic Modeling of Ligands in Cryo-EM Maps Using Deep Learning},
  author       = {Li, Shu and Jain, Anika and Kagaya, Yuki and Park, Joon Hong and Kihara, Daisuke},
  journal      = {bioRxiv},
  year         = {2026},
  doi          = {10.64898/2026.06.01.729423},
  url          = {https://www.biorxiv.org/content/10.64898/2026.06.01.729423v1},
  note         = {Preprint}
}