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[Demonstration of tumor inhibiting properties of a strongly immunostimulating low-molecular weight substance. Comparative studies with ifosfamide on the immuno-labile DS carcinosarcoma. Stimulation of the autoimmune activity for approx. 20 days by BA 1, a N-(2-cyanoethylene)-urea. Novel prophylactic possibilities].
A report is given on the recent discovery of outstanding immunological properties in BA 1 [N-(2-cyanoethylene)-urea] having a (low) molecular mass M = 111.104. Experiments in 214 DS carcinosarcoma bearing Wistar rats have shown that BA 1, at a dosage of only about 12 percent LD50 (150 mg kg) and negligible lethality (1...
22
[ -0.1952481, 0.02662686, -0.2887376, -0.4962555, 0.2272979, -0.2937426, 0.06150151, 0.1216393, 0.08873644, 0.004766163, -0.2030936, -0.04216306, 0.301732, 0.1281914, -0.5136515, -0.01254059, -0.05069955, -0.114424, 0.4553766, 0.7775063, 0.3281478, 0.1710027, -0.08429673, ...
The effect of o-salicylate upon pentose phosphate pathway activity in normal and G6PD-deficient red cells.
The effect of the major metabolite of aspirin, namely salicylic acid, upon the pentose phosphate pathway (PPP) of normal and G6PD-deficient red cells has been studied. Salicylic acid was shown to inhibit this pathway in proportion to the amount present. At any concentration of this substance there was greater inhibitio...
35
[ -0.1174217, -0.02674222, -0.08777715, -0.1448969, 0.09645668, 0.02517103, 0.09585091, 0.0344965, -0.09925366, -0.1455042, 0.08980603, 0.5076284, -0.3762439, 0.04054961, -0.6758007, 0.2132524, -0.3338553, 0.2121315, 0.02502716, 0.3889699, 0.437962, 0.1962271, 0.04635986, ...
Purification and properties of Escherichia coli dihydrofolate reductase.
Dihydrofolate reductase has been purified 40-fold to apparent homogeneity from a trimethoprim-resistant strain of Escherichia coli (RT 500) using a procedure that includes methotrexate affinity column chromatography. Determinations of the molecular weight of the enzyme based on its amino acid composition, sedimentation...
46
[ -0.04975511, 0.02799446, -0.0799185, -0.3373086, 0.1156839, -0.2492864, -0.06095669, 0.0480009, 0.08117862, -0.06972822, 0.2196043, 0.2009295, 0.1419505, 0.5185277, -0.4655703, 0.1586056, -0.3999305, 0.2749534, -0.02884772, 0.5770271, 0.09230841, -0.04334556, 0.1195075, ...
Bile acids. XLVII. 12alpha-Hydroxylation of precursors of allo bile acids by rabbit liver microsomes.
Rabbit liver microsomal preparations fortified with 0.1 mM NADPH effectively promote hydroxylation of [3beta-3H]- or [24-14C]allochenodeoxycholic acid or [5alpha,6alpha-3H2]5alpha-cholestane-3alpha,7alpha-diol to their respective 12alpha-hydroxyl derivatives in yields of about 25 or 65% in 60 min. Minor amounts of othe...
65
[ -0.01889459, 0.1867609, -0.5301204, -0.03484135, 0.07061984, -0.317839, -0.1689263, -0.01725332, -0.1425, 0.02560662, 0.004045904, 0.178752, 0.2434982, 0.01926355, -0.5574934, -0.1864285, -0.5344681, 0.1942875, -0.2061748, 0.2014778, 0.302605, 0.3513287, -0.05928331, 0....
Myosin from arterial smooth muscle: isolation following actin depolymerization.
The contractile proteins from arterial smooth muscle are highly soluble, and can be extracted at I = 0.05. However, they can be precipitated by a prolonged dialysis at pH 6 to give an actomyosin with a high, although variable, actin:myosin ratio. The sedimentation behavior of this actomyosin at high ionic strength was ...
85
[ -0.1912857, -0.01225896, -0.3340225, 0.2776466, 0.2724117, -0.01681103, -0.2871037, 0.2493768, 0.09911431, -0.06917986, -0.009765179, -0.06640607, 0.0581364, 0.07542987, -0.4336599, -0.09239094, -0.3772136, 0.2283605, 0.03566631, 0.4736768, 0.3887511, 0.0456669, -0.030791...
Polymer concentration dependence of the helix to random coil transition of a charged polypeptide in aqueous salt solution.
The helix to coil transition of poly(L-glutamic acid) was investigated in 0.05 and 0.005 M aqueous potassium chloride solutions by use of potentiometric titration and circular dichroism measurement. Polymer concentration dependence of the transition was observed in the range from 0.006 to 0.04 monomol/e in 0.005 M KG1 ...
96
[ -0.05710771, 0.05410222, -0.3442596, 0.05992413, 0.07951389, -0.2155136, -0.1654641, 0.06015636, -0.0936703, 0.4405082, 0.04600148, 0.3412398, 0.1015594, 0.2003551, -0.1965826, 0.007277522, -0.442699, 0.477363, -0.1535186, 0.09682028, 0.6429498, -0.2365454, 0.2728004, 0...
Inhibitory postsynaptic actions of taurine, GABA and other amino acids on motoneurons of the isolated frog spinal cord.
The actions of glycine, GABA, alpha-alanine, beta-alanine and taurine were studied by intracellular recordings from lumbar motoneurons of the isolated spinal cord of the frog. All amino acids tested produced a reduction in the amplitude of postsynaptic potentials, a blockade of the antidromic action potential and an in...
128
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Effects of zinc-smelter emissions on forest soil microflora.
Within 2 km of a zinc (Zn) smelter in Palmerton, Pennsylvania, near the Lehigh Water Gap, up to 13.5% Zn by weight has been measured in the O2 horizon of the soil, and up to 8% Zn in the A1 horizon. The total numbers of bacteria, actinomycetes, and fungi (measured by dilution plate counts) were greatly reduced in the m...
142
[ -0.07275498, -0.3921451, 0.03908189, -0.05747085, -0.5404968, 0.2207332, -0.2841226, -0.0966987, -0.1507201, -0.4263017, -0.4357284, -0.07479189, 0.01977523, 0.2588255, -0.1971188, 0.2621723, -0.1802516, 0.2396335, 0.1862607, 0.2683917, 0.2241954, 0.5736347, 0.1555335, ...
Effects of decreasing arterial blood pressure on cerebral blood flow in the baboon. Influence of the sympathetic nervous system.
The influence of the sympathetic nervous system on the cerebral circulatory response to graded reductions in mean arterial blood pressure was studied in anesthetized baboons. Cerebral blood flow was measured by the 133Xe clearance method, and arterial blood pressure was decreased by controlled hemorrhage. In normal bab...
153
[ -0.09153596, -0.08279135, -0.3971686, -0.4625964, -0.03311981, -0.4587905, -0.3329136, -0.1574502, -0.1958889, -0.05684167, 0.01018673, -0.0403447, 0.09432752, -0.1228682, -0.1672055, -0.3744506, -0.1570796, 0.08846965, 0.1387134, 0.218163, 0.1804146, 0.1996945, 0.0342492...
Serum lactate dehydrogenase activity ratios with different substrates.
1. The lactate dehydrogenase activity of 89 sera from patients suffering myocardial infarction and of 55 sera from patients with hepatocellular damage was assayed under optimal conditions using pyruvate, alpha-oxobutyrate, hydroxypyruvate and glyoxylate as substrates. Activity was also measured with lactate as substrat...
159
[ -0.3825009, 0.06541046, -0.281518, -0.1214671, -0.01831863, -0.2117968, -0.1351122, 0.1815567, -0.04896114, 0.001823694, 0.06683879, 0.07017197, -0.07058475, 0.3773852, -0.3083668, 0.1501622, -0.3888958, 0.2920901, 0.1260828, 0.5274778, 0.1005708, 0.2318961, 0.0142637, ...
Arterial catecholamines in hypoxic exercise in man.
1. We measured the minute ventilation and arterial blood catecholamine concentrations in four normal men standing and at two levels of moderate treadmill exercise breathing 14% oxygen or air. 2. Minute ventilation was significantly higher during hypoxic exercise than during normoxic exercise at an oxygen uptake of 1500...
171
[ -0.3157565, 0.1942144, -0.4225592, -0.2652202, 0.009740127, -0.2880788, -0.3225006, -0.2791676, -0.198275, -0.3810252, 0.07371543, 0.02130715, 0.03179343, -0.1090125, -0.04948851, -0.3446876, -0.3363214, 0.3402317, -0.03680023, 0.06858549, -0.1462419, 0.03348268, 0.090802...
An evaluation of factors affecting the in vitro bioassay for erythropoietin.
Two main aspects of the in vitro mouse foetal liver cell assay for Erythroid Stimulating Factor (ESF) in human sera have been investigated. The haem extraction process has been shown to give specific and quantitative recovery of 59Fe labelled haem from haemoglobin thus confirming that the material assayed in human sera...
250
[ -0.1565823, 0.1805312, -0.2313902, 0.06241505, 0.2058959, -0.1184516, 0.1942315, 0.2345746, 0.008648459, -0.01163057, -0.102793, 0.2746682, 0.222, -0.09215119, -0.4219195, -0.227127, -0.1771748, -0.1942768, -0.4250869, 0.8177173, 0.3049936, 0.06512058, -0.1958857, -0.16...
[Synthesis of N-substituted isoindolines].
Some derivatives of isoindoline were prepared in order to test their cardiovascular activity. Pharmacological tests showed that some of the compounds had moderate alpha-blocking and coronarodilatory activity whereas others had some local anesthetic activity.
251
[ -0.2874499, 0.03378921, -0.2687944, 0.008310201, 0.01565976, -0.02511024, -0.5212948, -0.01188042, 0.02308648, -0.2877338, 0.1474645, 0.0736376, 0.2223787, 0.1205716, -0.5163505, -0.1552203, -0.6457516, 0.158897, 0.1616492, 0.5406578, 0.2234828, -0.1169861, -0.07089421, ...
Gluconic acid production by Penicillium puberulum.
Twenty-five Penicillium species isolated from Egyptian soil were examined for their ability to produce gluconic acid in surface culture. Of the eight species capable of producing gluconic acid, Penicillium puberulum gave the maximum yield (91% gluconic acid from glucose after 7 days of fermentation with 3% CaCO3). Pept...
288
[ 0.04222201, -0.6275591, -0.08027469, 0.2738069, -0.04229129, 0.3489154, -0.2414041, 0.01325219, 0.03005599, -0.3787593, -0.03650443, -0.2886755, -0.2123309, 0.1000339, -0.5708048, 0.01672076, -0.6070583, 0.01039251, -0.1179466, -0.1023097, 0.7753011, 0.4043945, 0.1187844,...
Phenomenon of hot-cold hemolysis: chelator-induced lysis of sphingomyelinase-treated erythrocytes.
Staphylococcus aureus produces a phospholipase C specific for sphingomyelin (beta-hemolysin). Erythrocytes with approximately 50% sphingomyelin in their membranes, e.g., from sheep, have been shown to have up to 60% of this phospholipid hydrolyzed by this enzyme at 37 C in isotonic buffered saline without hemolysis. Co...
333
[ -0.06963796, -0.239983, -0.21175, -0.1077155, -0.2333045, -0.03663319, 0.004564053, -0.01489104, 0.0766198, -0.2624859, -0.0176843, 0.4612855, -0.1304457, -0.03970223, 0.1194658, -0.007164466, -0.2703684, -0.1243218, 0.03732867, 0.3341296, 0.238468, 0.341141, -0.2473686, ...
Degradation of myxovirus virion RNA by periodate.
Extensively degraded RNA was isolated from virions of influenza virus which had been oxidized with sodium m-periodate. Similarly, although to a lesser extent, RNA isolated from periodate-treated ribonucleoprotein of influenza virus was also degraded. In contrast, influenza virus RNA, if first freed from other virion co...
344
[ -0.3532551, -0.1579782, -0.236268, -0.07379157, -0.02147457, -0.1364446, -0.1562582, 0.03833071, -0.04239039, -0.3302781, 0.2010915, 0.1481799, 0.152257, 0.09385319, -0.03047571, 0.1058153, 0.03396561, 0.09324945, 0.1529052, -0.01779227, 0.1921448, -0.1615909, -0.1696343,...
Phospholipase D activity of gram-negative bacteria.
A phospholipase hydrolyzing cardiolipin to phosphatidic acid and phosphatidyl glycerol was characterized in gram-negative bacteria but was absent in preparations of gram-positive bacteria, Saccharomyces cerevisiae, and rat liver mitochondria. In cell-free extracts of Escherichia coli, Salmonella typhimurium, Proteus vu...
360
[ -0.2503959, -0.1440042, -0.4299152, 0.3390924, -0.01931684, 0.07734865, -0.2799501, 0.1530996, -0.1802472, -0.1615784, 0.2555251, 0.1487119, 0.0590297, 0.09646955, -0.4849542, 0.2367442, -0.1229633, -0.001100634, -0.1048315, 0.3610836, 0.3164546, 0.02984561, 0.05958613, ...
Expression of the hut operons of Salmonella typhimurium in Klebsiella aerogenes and in Escherichia coli.
The normal hut (histidine utilization) operons, as well as those with mutations affecting the regulation of their expression, of Salmonella typhimurium were introduced on an F' episome into cells of S. typhimurium and Klebsiella aerogenes whose chromosomal hut genes had been deleted and into cells of Escherichia coli, ...
362
[ 0.08233647, -0.1468, -0.1481288, 0.1728189, 0.27761, -0.3387713, -0.04256216, -0.1764247, 0.1135483, 0.172333, 0.1543974, 0.0567967, -0.1148193, 0.09158608, -0.9308323, -0.13314, -0.7695488, -0.0117861, -0.2240122, -0.1808263, 0.1931936, 0.02051953, -0.0698425, -0.24906...
Transport of molybdate by Clostridium pasteurianum.
The transport of 99MoO42- into dinitrogen-fixing cells of Clostridium pasteurianum was investigated. Transport of molybdate in this organism is energy dependent; sucrose is required in the minimal media, and the system is inhibited by the glycolysis inhibitors, NaF, iodoacetic acid, and arsenate. The cells accumulate m...
364
[ -0.5476305, -0.1116983, -0.09507642, 0.05556102, -0.1092918, 0.06983122, 0.1694483, 0.4066414, -0.1957953, -0.217406, 0.1453207, 0.1131561, 0.2592996, -0.08617747, -0.5403935, -0.2453799, -0.3824559, -0.003228049, -0.1788588, 0.3707748, 0.2539598, 0.3097678, -0.05594714, ...
D-Lactate dehydrogenase of Peptostreptococcus elsdenii.
D-Lactate dehydrogenase has been purified to near homogeneity from Peptostreptococcus elsdenii. As isolated, the enzyme contains flavine adenine dinucleotide and a tightly bound metal cofactor. Inactivation by ortho-phenanthroline occurs in two steps and is partially blocked by D-lactate. Reactivation by divalent metal...
368
[ -0.2555043, -0.05758644, -0.05783184, 0.3172738, 0.06464285, -0.4320138, -0.1071923, 0.1110315, -0.2355965, -0.007951145, 0.1192176, 0.1338026, 0.07533104, 0.1132957, -0.819092, 0.04019565, -0.5245284, 0.0577787, -0.1484597, 0.05629096, 0.1640314, 0.1242976, 0.005719058, ...
Studies on trypsin inhibitor in barley. I. Purification and some properties.
To clarify the properties and functions of a trypsin inhibitor from Japanese barley in comparison with the inhibitor from Pirkka barley, an inhibitor was isolated from the barley Hordeum distichum L var. emend Lamark by extraction with 1% NaCl, ammonium sulfate fractionation and repeated chromatography on DEAE-cellulo...
380
[ -0.1666157, 0.1373733, 0.3150953, -0.2093225, -0.2697855, -0.02237866, -0.09451506, -0.02869226, 0.2970838, 0.1377713, -0.1500842, 0.2130687, 0.43827, -0.1664164, -0.1832612, 0.5034396, -0.680441, 0.2289176, -0.04626885, 0.2753378, 0.2916314, 0.4314087, -0.3772539, 0.27...
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PubMed Abstracts Subset with MedCPT Embeddings (float32)

This dataset contains a probabilistic sample of ~2.4 million PubMed abstracts, enriched with precomputed dense embeddings (title + abstract), from the ncbi/MedCPT-Article-Encoder model. It is derived from public metadata made available via the National Library of Medicine (NLM) and was used in the paper Efficient and Reproducible Biomedical QA using Retrieval-Augmented Generation.

Each entry includes:

  • title: Title of the publication
  • abstract: Abstract content
  • PMID: PubMed identifier
  • embedding: 768-dimensional float32 vector from MedCPT

πŸ” How to Access

▢️ Option 1: Load via Hugging Face datasets

from datasets import load_dataset

dataset = load_dataset("slinusc/PubMedAbstractsSubsetEmbedded", streaming=True)

for doc in dataset:
    print(doc["PMID"], doc["embedding"][:5])  # print first 5 dims
    break

Each vector is stored as a list of 768 float32 values (compact, no line breaks).


πŸ’Ύ Option 2: Git Clone with Git LFS

git lfs install
git clone https://huggingface.co/datasets/slinusc/PubMedAbstractsSubsetEmbedded
cd PubMedAbstractsSubsetEmbedded

πŸ“¦ Format

Each file is a .jsonl (JSON Lines) file, where each line is a valid JSON object:

{
  "title": "...",
  "abstract": "...",
  "PMID": 36464820,
  "embedding": [-0.1952481, ... , 0.2887376]
}

The embeddings are 768-dimensional dense vectors, serialized as 32-bit floats.


πŸ“š Source and Licensing

This dataset is derived from public domain PubMed metadata (titles and abstracts), redistributed in accordance with NLM data usage policies.
MedCPT embeddings were generated using the ncbi/MedCPT-Article-Encoder model.


πŸ“£ Citation

If you use this dataset or the included MedCPT embeddings, please cite:

Stuhlmann et al. (2025)
Efficient and Reproducible Biomedical Question Answering using Retrieval Augmented Generation
arXiv:2505.07917
https://github.com/slinusc/medical_RAG_system


🏷️ Version

  • v1.0 – Initial release (2.39M samples, 24 JSONL files, float32 embeddings, ~23 GB total)

πŸ“¬ Contact

Maintained by @slinusc.
For questions or collaborations, open a discussion on the HF Hub.

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